After seeing this recipe, I am never making this any other way again!

This Mac and Cheese Meatloaf Casserole is the ultimate comfort food mashup, combining a savory, BBQ-glazed meatloaf base with a creamy, cheesy layer of macaroni. It’s a hearty, all-in-one meal perfect for family dinners.

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Mac and Cheese Meatloaf Casserole

Ingredients:

For the Meatloaf Layer Quantity
Ketchup 1 cup
Sweet Baby Ray’s Hickory & Brown Sugar Barbecue Sauce 1 cup
Lean Ground Beef 2 lbs
Ritz Crackers (crushed) 30
Lipton Onion Soup Mix (dry) 2 oz
Eggs 2
Salt 1 tsp
Pepper 1 tsp
Garlic Powder 1 tbsp
Onion Powder 1 tbsp
For the Mac and Cheese Layer:
Ingredient Quantity
Milk 2 cups
Condensed Cheddar Cheese Soup 10.5 oz
Macaroni Noodles 3 cups
Salt, Pepper, Garlic Powder, Onion Powder (use amount from meatloaf mix) To taste
Ingredient Quantity
Ketchup and Barbecue Sauce Mixture (remaining from step 2) Remaining 1/2 cup
Shredded Mozzarella and Cheddar Cheese Blend 4 cups (2 cups stirred into Mac & Cheese, 2 cups for topping)

How To Make Mac and Cheese Meatloaf Casserole:

  1. Step 1: Preheat and Prepare: Preheat your oven to 350°F (175°C). Grease a 9×13 inch baking dish.
  2. Step 2: Sweet and Tangy Sauce: In a medium bowl, whisk together the 1 cup ketchup and 1 cup barbecue sauce. You will use 1/2 cup now and 1/2 cup later.
  3. Step 3: Meatloaf Mixture: In a large bowl, combine the ground beef, crushed Ritz Crackers, Lipton onion soup mix, eggs, 1/2 cup of the ketchup and barbecue sauce mixture, 1 tsp salt, 1 tsp pepper, 1 tbsp garlic powder, and 1 tbsp onion powder. Mix everything well until fully incorporated.
  4. Step 4: Forming and Glazing the Meatloaf Layer: Press the seasoned meatloaf mixture evenly into the prepared baking dish. Spread the remaining 1/2 cup of the ketchup and barbecue sauce mixture on top of the meatloaf layer.
  5. Step 5: Bake the Meatloaf Layer: Bake the meatloaf layer in the preheated oven for 30 minutes.
  6. Step 6: Cooking the Macaroni: While the meatloaf layer is baking, cook the macaroni noodles according to the package directions. Once cooked, drain the noodles.
  7. Step 7: Cheesy Mac and Cheese Mixture: In a large bowl, whisk together the milk and condensed cheddar cheese soup until smooth and creamy. Stir in the cooked macaroni noodles, 2 cups of the shredded cheese blend, and seasoning (salt, pepper, garlic powder, and onion powder to taste).
  8. Step 8: Assembling the Casserole: Take the baking dish out of the oven after the 30 minutes. Carefully pour the mac and cheese mixture on top of the meatloaf layer, spreading it evenly.
  9. Step 9: Cheese Topping and Final Bake: Sprinkle the remaining 2 cups of shredded cheese blend over the top of the mac and cheese layer. Bake the casserole for an additional 17-20 minutes, or until the cheese is melted, bubbly, and slightly golden brown.
  10. Step 10: Serving: Let the casserole cool for a few minutes before slicing and serving. Enjoy!

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