Southern Five Layer Beef Casserole

Step into the heart of Southern comfort with this Southern Five-Layer Beef Casserole, a warm, hearty dish that brings layers of bold flavors together in perfect harmony. Imagine tender beef, rich cheese, and aromatic spices melding into a golden, bubbling delight. Whether you’re gathering with family or preparing a cozy dinner for two, this recipe delivers the kind of homemade goodness that turns meals into memories.

A Southern Tradition

Rooted in generations of Southern home cooking, this casserole is more than just a dish—it’s a legacy of love and togetherness. Passed down through families, it blends tradition with modern convenience, making it a go-to favorite for celebrations, potlucks, or casual weeknight dinners.

Ingredients

✅ Customizations: Want more spice? Add jalapeños! Going vegetarian? Swap the beef for tofu crumbles or plant-based meat alternatives.

Instructions

1. Preheat & prep – Set your oven to 375°F and grease a baking dish.
2. Cook the beef – In a skillet, brown ground beef with chopped onions and green bell peppers. Drain excess fat.
3. Build the flavors – Stir in tomato sauce, garlic powder, salt, and pepper. Simmer for 10 minutes.
4. Prepare the batter – In a separate bowl, mix biscuit baking mix, milk, and eggs to form a thick batter.
5. Start layering – Spread half of the batter in the baking dish, then add half of the beef mixture and cheese.
6. Repeat – Build another layer, finishing with cheese on top.
7. Bake to perfection – Bake for 25-30 minutes, until golden and bubbling.
8. Serve & enjoy – Let it cool slightly, then dig into layers of cheesy, savory goodness!

💡 Pro Tip:

• Want extra crispiness? Bake uncovered for the last 5 minutes.
• Prefer a softer texture? Let the casserole rest for 10 minutes before serving.
• Experiment with different cheeses for a unique twist!